Dr. Tiffany Delacruz, DVM • Chief Executive Officer, RexVet • 2026-07-04 • 6 min read
Get Heartgard Plus Prescription Online — $64.99 FL, NY & VA Licensed Vets | RexVet
Get a Heartgard Plus prescription online for your dog in Florida, New York, or Virginia. Licensed DVMs prescribe monthly heartworm+intestinal worm chewable by $64.99 video visit.
Medically reviewed by Dr. Tiffany Delacruz, DVM
Book your $64.99 online vet visit now
RexVet's licensed DVMs prescribe Heartgard Plus for qualifying dogs in Florida, New York and Virginia via $64.99 video visit. Heartgard Plus is the longest-standing monthly heartworm chewable — trusted by 3 generations of vets.
What Heartgard Plus protects against
- Heartworm disease (Dirofilaria immitis) — prevents heartworm infection when given monthly
- Roundworms (Toxocara canis, Toxascaris leonina) — treats and controls
- Hookworms (Ancylostoma caninum, Uncinaria stenocephala) — treats and controls
- Does NOT protect against fleas, ticks, or whipworms — pair with a flea/tick product
Why heartworm prevention matters year-round in FL/NY/VA
Heartworm disease is transmitted by mosquitoes. In Florida, mosquito season is 12 months per year. In New York and Virginia, mosquito season is 6-9 months, but treatment of heartworm-positive dogs costs $1,000-$3,000 and can be fatal. Standard-of-care is year-round monthly prevention in all 3 states. Missing doses creates an infection window and requires re-testing before restarting.
What to have ready for your video visit
- Your dog's weight
- Date and result of last heartworm test
- Current heartworm prevention product and last dose
- Your dog's breed — MDR1 gene testing may be worth discussing for Collies, Aussies, Shelties
- Your dog's age
Dosing by dog weight
- Up to 25 lbs: 68 mcg / 57 mg chewable (blue box)
- 26-50 lbs: 136 mcg / 114 mg chewable (green box)
- 51-100 lbs: 272 mcg / 227 mg chewable (brown box)
- 101+ lbs: use appropriate combination — vet-guided
- One chewable per month, same day each month (set a phone reminder)
Side effects and safety
- Very well tolerated — Heartgard Plus has one of the best safety profiles in veterinary medicine
- Rare: mild vomiting, decreased appetite, lethargy
- Overdose can cause neurologic signs — this is very rare with labeled dosing
- Safe for MDR1-positive dogs (Collies, Aussies, Shelties) at labeled Heartgard Plus dose
- Safe from 6 weeks of age
Cost transparency
$64.99 for the RexVet video visit. A 6-pack of Heartgard Plus typically costs $40-$70 depending on dog weight — filled at Chewy, Costco, or local vet retail. Total 6-month cost with one video visit typically $105-$135. Very affordable relative to $1,000-$3,000 heartworm treatment if your dog gets infected.
About Dr. Tiffany Delacruz — Chief Executive Officer
Our video visits are led by Dr. Tiffany Delacruz, DVM, and our licensed DVM team. Dr. Tiffany is licensed to practice veterinary medicine in Florida, New York and Virginia. She has managed heartworm prevention programs for years across the highest-risk mosquito states in the US.
Emergency signals
When to contact a veterinarian
- Missed multiple doses — re-testing may be needed before restarting
- Symptoms of heartworm disease: cough, exercise intolerance, weight loss, fainting
- Adverse reaction to Heartgard Plus (very rare) — mild vomiting or lethargy usually self-resolves
- MDR1-positive breed — dosing needs careful attention
Frequently asked questions
Can an online vet prescribe Heartgard Plus?
Yes — RexVet's licensed DVMs in Florida, New York and Virginia can prescribe Heartgard Plus during a $64.99 video visit after a negative heartworm test is confirmed. A valid veterinarian-client-patient relationship is established during the visit.
Do I need a heartworm test before starting Heartgard Plus?
Yes — a negative heartworm test from within the last 12 months is required before starting or restarting prevention. If it's been longer, we'll recommend a local vet clinic for testing. Testing is a $50-$100 in-clinic procedure that takes 10 minutes.
How much does Heartgard Plus cost?
The RexVet video visit is $64.99. A 6-pack of Heartgard Plus typically costs $40-$70 filled at Chewy, Costco Pet Pharmacy, or local vet retail. Total annual cost with 2 doses of the 6-pack: $80-$140 medication + $64.99 video visit = ~$150-$205 per year for heartworm prevention.
Do I need year-round Heartgard Plus in NY/VA?
Yes — American Heartworm Society recommends year-round prevention in all 50 states. Even in colder northern states, warmer winter days can allow mosquito activity, and missed doses create infection windows that require expensive re-testing to safely restart.
Is Heartgard Plus safe for my Collie or Aussie Shepherd?
Yes at labeled dose. Heartgard Plus is safe for MDR1-positive dogs (Collies, Aussies, Shelties, Old English Sheepdogs, Whippets) at the standard labeled dose. Higher doses used off-label are riskier — always follow prescribed dosing.
Do I still need flea and tick prevention if my dog is on Heartgard Plus?
Yes — Heartgard Plus does NOT protect against fleas or ticks. Pair it with a flea/tick product like NexGard, Bravecto, or Simparica. Or ask about NexGard Plus and Simparica Trio, which combine both into one chewable.
Which states can RexVet prescribe Heartgard Plus in?
Florida, New York, and Virginia — where our vets are licensed. Outside these three states, our vets cannot legally prescribe.
Continue reading
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About the author
Dr. Tiffany Delacruz, DVM
Chief Executive Officer, RexVet
Licensed veterinarian and CEO of RexVet (Rex Vets Inc.). Practicing across Florida, New York, and Virginia via licensed telehealth. Reviews every clinical article on RexVet before publication.