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Medication Guide • Reviewed by Dr. Tiffany Delacruz, DVM

Cerenia for Cats

Cerenia is a prescription anti-nausea medication for cats that controls vomiting from various causes — chemotherapy, kidney disease, motion sickness, or acute GI upset.

Generic: maropitant citrate Class: Neurokinin-1 (NK-1) receptor antagonist Prescription required FDA-approved for cats
Important: This page is an educational reference. Never start, stop, or change your pet's medication without veterinary guidance. Specific dosing depends on your pet's weight, condition, and other medications. To get a personalized prescription or refill, talk to a licensed RexVet veterinarian.

What Cerenia is used for in cats

  • Acute vomiting from various causes
  • Chemotherapy-induced nausea
  • Chronic kidney disease nausea support
  • Pre-procedure / post-surgical nausea

How it works

Maropitant blocks NK-1 receptors in the brain's vomiting center, stopping nausea at the signal source.

Available formulations

16 mg tablet

Injectable solution

Side effects to know

Common side effects

  • Mild sedation
  • Decreased appetite
  • Drooling

These usually resolve on their own. If they persist past the first few doses, ask your vet.

Call your vet immediately if you see

  • Severe allergic reaction
  • Pain at injection site (injectable form)
  • Persistent lethargy

Drug interactions

  • Generally low; confirm with your vet on multi-medication plans

When not to use

  • Cats under 16 weeks (acute use)
  • Severe liver disease

Monitoring during treatment

Often used short-term for acute episodes. For chronic conditions (e.g. kidney disease), follow your vet's specific schedule.

Need a Cerenia refill?

RexVet is the first 501(c)(3) non-profit online vet service in the U.S. Talk to a licensed veterinarian by video, get your cats's Cerenia prescription, and have it shipped through RexVetRx — all for $64.99 per visit.

Book a vet visit — $64.99

Cerenia for Cats

Frequently asked questions

How fast does Cerenia work in cats?

Most cats stop vomiting within 1-2 hours of an oral dose. The injectable form works faster.

Can Cerenia be used long-term in cats with kidney disease?

Yes — chronic kidney disease cats often benefit from Cerenia for nausea management. Your vet will set the right schedule.

What if my cat won't swallow the Cerenia tablet?

Pill pockets, soft food, or asking your vet about a compounded liquid usually solves this. The injectable form is another option for difficult oral dosers.

Can RexVet prescribe Cerenia for my cat?

Yes — for acute vomiting, chronic kidney support, or post-procedure nausea, a RexVet video visit can ship Cerenia same-day through RexVetRx.

Should I worry about ongoing vomiting in my cat?

Vomiting more than twice in 24 hours, or any vomiting in a cat that's also lethargic or not eating, needs veterinary attention quickly — Cerenia treats the symptom but the cause matters.

Medical review by Dr. Tiffany Delacruz, DVM

Chief Executive Officer & Lead Veterinarian, RexVet. Licensed in Florida, New York, and Virginia.

Last fact-checked: 2026-05-19

Sources

This page is an educational reference and does not replace veterinary advice. Always consult a licensed veterinarian before starting, changing, or stopping medication for your pet.