Medication Guide • Reviewed by Dr. Tiffany Delacruz, DVM
Galliprant for Dogs
Galliprant is a prescription medication for osteoarthritis pain in dogs. It works through a more targeted mechanism than traditional NSAIDs, potentially with fewer GI side effects.
What Galliprant is used for in dogs
- Osteoarthritis pain and inflammation in dogs
How it works
Galliprant blocks the EP4 prostaglandin receptor — the specific receptor most involved in osteoarthritis pain — without broadly inhibiting other prostaglandin pathways that traditional NSAIDs affect.
Available formulations
20 mg tablet
60 mg tablet
100 mg tablet
Side effects to know
Common side effects
- • Vomiting
- • Decreased appetite
- • Diarrhea
- • Lethargy
These usually resolve on their own. If they persist past the first few doses, ask your vet.
Call your vet immediately if you see
- ⚠ Black/tarry stools
- ⚠ Bloody vomit
- ⚠ Severe lethargy
- ⚠ Yellow gums or eyes
Drug interactions
- • Other NSAIDs (do not combine)
- • Corticosteroids (do not combine)
- • ACE inhibitors (with kidney monitoring)
When not to use
- • Dogs under 9 months or 8 lbs
- • Concurrent NSAID or steroid therapy
- • Severe kidney or liver disease
- • Dehydrated dogs
Monitoring during treatment
Baseline bloodwork is recommended. Watch for any GI, liver, or kidney side effects.
Need a Galliprant refill?
RexVet is the first 501(c)(3) non-profit online vet service in the U.S. Talk to a licensed veterinarian by video, get your dogs's Galliprant prescription, and have it shipped through RexVetRx — all for $64.99 per visit.
Book a vet visit — $64.99Galliprant for Dogs
Frequently asked questions
How is Galliprant different from Rimadyl?
Galliprant targets a single prostaglandin receptor specific to arthritis pain, while Rimadyl is a broader COX-2 inhibitor. Galliprant may be gentler on the stomach and kidneys, but every dog is different.
How fast does Galliprant work?
Most dogs show pain improvement within 24-48 hours. The full effect typically develops over 1-2 weeks.
Can Galliprant be given with other medications?
Yes — Galliprant is often combined with gabapentin or joint supplements for multi-modal arthritis management. But never combine with NSAIDs or steroids without vet supervision.
Can RexVet prescribe Galliprant?
Yes, for dogs with a current arthritis diagnosis and bloodwork. RexVet video visits can manage long-term arthritis cases including Galliprant refills through RexVetRx.
Is Galliprant safe for senior dogs?
Yes — senior dogs are the largest user group for Galliprant. Periodic bloodwork helps catch any age-related kidney or liver changes.
Medical review by Dr. Tiffany Delacruz, DVM
Chief Executive Officer & Lead Veterinarian, RexVet. Licensed in Florida, New York, and Virginia.
Last fact-checked: 2026-05-19
Sources
This page is an educational reference and does not replace veterinary advice. Always consult a licensed veterinarian before starting, changing, or stopping medication for your pet.