Medication Guide • Reviewed by Dr. Tiffany Delacruz, DVM
Drontal Plus for Dogs
Drontal Plus is a prescription dewormer that kills the most common intestinal worms in dogs — roundworms, hookworms, whipworms, and tapeworms — in a single dose.
What Drontal Plus is used for in dogs
- Roundworm infection
- Hookworm infection
- Whipworm infection
- Tapeworm infection
How it works
The three active ingredients work together to paralyze and kill different worm classes in the GI tract. Worms are then passed through the stool.
Available formulations
Flavored chewable tablets in multiple sizes
Side effects to know
Common side effects
- • Mild vomiting
- • Decreased appetite
- • Diarrhea
These usually resolve on their own. If they persist past the first few doses, ask your vet.
Call your vet immediately if you see
- ⚠ Severe vomiting or diarrhea
- ⚠ Allergic reaction (rare)
Drug interactions
- • Minimal — confirm with your vet if your dog is on multiple medications
When not to use
- • Pregnant dogs (consult vet)
- • Severely debilitated or sick dogs
Monitoring during treatment
Drontal kills adult worms but not eggs. Repeat dosing or fecal recheck may be needed depending on the worm type.
Need a Drontal Plus refill?
RexVet is the first 501(c)(3) non-profit online vet service in the U.S. Talk to a licensed veterinarian by video, get your dogs's Drontal Plus prescription, and have it shipped through RexVetRx — all for $64.99 per visit.
Book a vet visit — $64.99Drontal Plus for Dogs
Frequently asked questions
How often should I deworm my dog?
Puppies typically need deworming every 2-3 weeks until 12 weeks of age. Adult dogs at risk (outdoor, hunting, multi-pet households) often need quarterly deworming. Many monthly heartworm preventives also include intestinal worm coverage.
Will I see worms after giving Drontal?
Sometimes — you may see dead worms in the stool for 1-3 days after dosing. This is normal and means it's working.
Can RexVet prescribe Drontal?
Yes — with a recent fecal exam confirming worms (or strong clinical suspicion). RexVet can ship Drontal through RexVetRx.
Do I need to repeat the dose?
Often yes — for some worms, a second dose 2-3 weeks later catches worms that were eggs during the first dose. Your vet will advise based on the specific infection.
Should I bring a fresh stool sample to confirm worms?
Yes — a fecal float test is the standard way to confirm worm type and severity. Many vets can do it same-day in-house.
Medical review by Dr. Tiffany Delacruz, DVM
Chief Executive Officer & Lead Veterinarian, RexVet. Licensed in Florida, New York, and Virginia.
Last fact-checked: 2026-05-19
Sources
This page is an educational reference and does not replace veterinary advice. Always consult a licensed veterinarian before starting, changing, or stopping medication for your pet.