Medication Guide • Reviewed by Dr. Tiffany Delacruz, DVM
Bravecto for Dogs
Bravecto is an every-3-month (12-week) chewable or topical that kills fleas and ticks in dogs. It's the longest-acting isoxazoline available.
What Bravecto is used for in dogs
- Flea prevention for 12 weeks per dose
- Tick prevention
- Mite control (some formulations)
How it works
Fluralaner blocks parasite nerve receptors and persists in the bloodstream for 12 weeks, providing long-duration flea and tick kill.
Available formulations
Flavored chewable, every 12 weeks
Topical spot-on
Side effects to know
Common side effects
- • Mild vomiting
- • Decreased appetite
These usually resolve on their own. If they persist past the first few doses, ask your vet.
Call your vet immediately if you see
- ⚠ Neurologic signs (tremors, ataxia, seizures — rare)
- ⚠ Severe lethargy
Drug interactions
- • Consult your vet for dogs on seizure medications
When not to use
- • Puppies under 6 months or 4.4 lbs
- • Dogs with seizure history (use cautiously)
- • Dogs with documented isoxazoline sensitivity
Monitoring during treatment
First dose should be observed for 24 hours. Because the dose covers 12 weeks, side effects may be longer-lasting if they occur.
Need a Bravecto refill?
RexVet is the first 501(c)(3) non-profit online vet service in the U.S. Talk to a licensed veterinarian by video, get your dogs's Bravecto prescription, and have it shipped through RexVetRx — all for $64.99 per visit.
Book a vet visit — $64.99Bravecto for Dogs
Frequently asked questions
How often is Bravecto given to dogs?
Every 12 weeks (about 4 times per year), making it one of the most convenient flea and tick options for dogs.
How fast does Bravecto start working?
Fleas start dying within 2 hours; ticks within 12 hours. Full coverage is established within 24 hours of the first dose.
Is Bravecto safe long-term?
Bravecto has been on the market since 2014 with extensive post-market safety data. Most dogs tolerate it well. As with any isoxazoline, dogs with seizure history should be evaluated case-by-case.
Can RexVet prescribe Bravecto?
Yes. A RexVet video visit and we can ship Bravecto every 12 weeks through RexVetRx automatically.
Can I bathe my dog after Bravecto?
Yes. The oral chewable isn't affected by bathing. The topical spot-on should not be washed off for 72 hours after application.
Medical review by Dr. Tiffany Delacruz, DVM
Chief Executive Officer & Lead Veterinarian, RexVet. Licensed in Florida, New York, and Virginia.
Last fact-checked: 2026-05-19
Sources
This page is an educational reference and does not replace veterinary advice. Always consult a licensed veterinarian before starting, changing, or stopping medication for your pet.